Biomedical Engineering Laboratory, Department of Mechanical Engineering, Kogakuin University

Biomedical Engineering Laboratory, Department of Mechanical Engineering, Kogakuin University
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Medical treatment and diagnosis are supported by engineering. New technology develops new medical treatment: artificial organs, biomaterials, regenerative medicine. Engineering is important to design new artificial organs: mechanical engineering, electrical engineering, materials engineering. Every part of body communicates with the other parts of body through unknown biological networks, which controls the biological system.

            

Introduction

Cell Culture Technique

The facilities of clean area enable cell culture experiments. Cells are used for each research project.

            
cleanbench
Cell Culture
Biomedical Engineering Research Center
Biomedical Engineering Research Center
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Machine Shop

Experimental devices are manufactured by students. The training grows their ability to design new things.

            
Turning Machine
Turning Machine
Machine Factory
Machine Factory
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International Exchange

Exchange program with Department of Biomedical Engineering abroad includes not only a scientific presentation contest, but also sightseeing.

            
Bangkok 200408
Bangkok
Chula bme lab 200408
Chula BME
Chula Seminar 200603
Chula Seminar
Chula Kyoto 200603
Chula Kyoto
UC Berkley
UC Berkley
northwestern
Northwestern
UIC
UIC
WMSCI
WMSCI
Chulabio2010
ChulaBME2010
Chula2013
Chula2013
Mahidol2010
Mahidol2010
Mahidol2013
Mahidol2013
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Research Projects

Application of Cultured Myotubes to Medical Engineering

The facilities of clean area enable cell culture experiments. Cells are used for each research project.

            
Myotubes
Myotubes
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Effect of Magnetic Field on Cell Culture

Magnetic field at low frequency might change normal cells to cancer cells. Electro-magnetic field generated from cellular phone might damage biological tissue. Effect of magnetic field on cells is measured using Helmholtz Coil. Another experimental system is designed with a mobile phone.

            
Magnetic Field
Magnetic Field
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Application of Laser Technique to Bio-measurement

Laser technique is applied to measure biological state of tissue. The reflected laser light might include biological information.

            
laser
Laser system
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Measurement of Impedance of Biological Tissue

Local properties might control biological activity in the tissue. Local impedance is measured with a specially designed electrode.

            
Electrode
Micro-electrode
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Effect of Shear flow on Endothelial Cells

Cells on the inner surface of a prosthetic vessel tube are observed under an optical microscope exposed controlled pulsatile flow of culture medium. The results are applied to design a blood flow path of artificial vessels or artificial blood pumps.

            
Cell in Flow
Cell in Flow
 
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Effect of Shear Field on Red Blood Cell Deformation

A red blood cell has great deformability to pass through microcirculation. Red blood cells can be damaged by an artificial blood pump. The deformed shape is measured under an optical microscope with the Rheoscope of counter rotating discs.

            
Red Blood Cell Deformation
Cell Deformation
 
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Application of Functional Microstructured Surface to Biomedical Engineering

A micro slit between micro columns has been made by photolithography technique. Biological cells can be filtered through the micro slit.

            
Micro Slit
Micro Slit
 
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